Jennifer Aniston, Alicia Keys, Demi MooreLarry Busacca/Getty Images for Lifetime

Jennifer Aniston, Alicia Keys and Demi Moore stepped out from behind the camera for the premiere of Five at Skylight SoHo in New York City. All three leading ladies directed a short film for the five-part Lifetime movie, which explores the impact of breast cancer on women and the people in their lives. (Watch it Monday, October 10th at 9/8c.) Click through the gallery to see more celebrities at last night’s hottest events!