Oprah's Most Beautiful MomentsLuis Guerra/Ramey Photo; Valerie Goodloe/Globe Photos; Dimitrios Kambouris/WireImage

Oprah Winfrey’s final show airs on Wednesday, and while the talk show queen has gone through her share of hairstyles (Pixies! Shags! Perms!) and trends (Shoulder pads! Cowboy boots!), she always returns to her fashion standbys. After 25 years on the air, Winfrey knows what works for her, and some of her signature styles include crisp button-downs paired with voluminous skirts (left), vibrant reds (center), and shades of blush and beige (right). Click through the gallery to see all of Oprah’s classic fashion moments. And tell us, what’s your favorite Oprah look?